The genetic analysis of model organisms has identified many of the regulatory pathways that control normal development whilst at the same time giving remarkable new insights into the molecular basis of human disease.

Developmental and pathological processes can now be analysed in vivo at the cellular and sub-cellular level using model organisms such as Drosophila, zebrafish and chick.

These organisms thus provide a powerful approach to the identification of novel candidates for genes underlying human disease and in addition provide powerful in vivo models for the functional analysis of the human genome and for drug discovery.

The principal strategy of the Centre for Developmental and Biomedical Genetics is to use these organisms to develop novel models of neurodegenerative, cardiovascular, musculo-skeletal disease and cancer.

• Biología
• Ciencias de la tierra
• Investigación