The Centre for Lung Health team is multi disciplinary and the investigators are involved in multiple areas of research. The major lung health research interests at the VCHRI Pulmonary and Critical Care Research Program are respiratory sleep and neuromuscular disease, environmental and occupational lung disease, lung cancer, tuberculosis and a broad program of clinical research in asthma, COPD, interstitial lung disease and pulmonary hypertension. An emerging program of research in respiratory health outcomes in these different disease categories is also being developed in collaboration with the Centre for Clinical Epidemiology and Evaluation at VGH and Centre for Health Evaluation Outcomes Sciences at St.Paul's Hospital (CHEOS) and there are substantial strengths in epidemiology and translational research at both Centres. The iCapture Centre at St. Paul's was created with CFI funds to examine how abnormal genes change the structure and function of cells, tissues and organs to cause lung disease. The prevention and early diagnosis of lung cancer is the primary research focus at the Vancouver Cancer Centre and research into tuberculosis and mycobacterial disease is the major interest at the BC Centre for Disease Control. Research in lung transplantation takes place at both Vancouver Acute and the BC Transplant Society. Finally, there is a established research link with Critical Care Medicine, and members are now holders of a joint Michael Smith Foundation grant on patient safety in Critical Care Units.